Lumixa
Inflammageing
"Inflammageing": how inflammation leads to ageing
The expression "inflammageing" refers to a continuous, low-level and asymptomatic inflammatory process associated with ageing.
This process is particularly triggered by exposure to UV rays, which induce oxidative stress and the production of pro-inflammatory cytokines
Such an inflammatory response could become chronic over time and gradually cause damage to skin tissues:
• inhibition of adaptation and repair mechanisms
• dehydration
• skin matrix weakening
• collagen and elastin degradation
• skin barrier impairment
• solar lentigo
Skin matrix weakening
Fibroblasts: cells that synthesize the support structure of the skin. They produce two main proteins:
• Collagen: an essential component of the skin that provides structural support.
• Elastin: gives elasticity and tone to the skin.
Collagen, together with elastin is responsible for the texture and elasticity of the skin.
Scientific studies show that as soon as we become adults, the overall percentage of collagen decreases by about 1% per year.
Degradation of collagen causes wrinkles and skin ageing.
